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Protocadherin 17 is a tumor suppressor and is frequently methylated in nasopharyngeal carcinoma

PURPOSE: Several PCDH genes were shown to be downregulated or silenced in carcinomas and act as candidate tumor suppressor genes. However, the functions of PCDH17 in nasopharyngeal carcinoma (NPC) remain unclear. Here, we investigated the PCDH17 promoter methylation status and its impact on the expr...

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Detalles Bibliográficos
Autores principales: He, Ya, Wang, Zhihai, Liu, Chuan, Gong, Zhitao, Li, Yanshi, Lu, Tao, Hu, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388982/
https://www.ncbi.nlm.nih.gov/pubmed/30863170
http://dx.doi.org/10.2147/CMAR.S191102