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Isoform specific gene expression analysis of KRAS in the prognosis of lung adenocarcinoma patients

BACKGROUND: Aberrant mutations in KRAS play a critical role in tumor initiation and progression, and are a negative prognosis factor in lung adenocarcinoma (LUAD). RESULTS: Using genomic analysis for K-Ras isoforms (K-Ras4A and K-Ras4B) and large-scale multi-omics data, we inspected the overall surv...

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Detalles Bibliográficos
Autores principales: Yang, In Seok, Kim, Sangwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389035/
https://www.ncbi.nlm.nih.gov/pubmed/29504894
http://dx.doi.org/10.1186/s12859-018-2011-y