A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity

BACKGROUND: The current BCG vaccine induces only short-term protection against Mycobacterium tuberculosis (Mtb), suggesting its failure to generate long-lasting memory T cells. Previously, we have demonstrated that a self-adjuvanting peptide of Mtb (L91), successfully generated enduring memory Th1 c...

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Detalles Bibliográficos
Autores principales: Rai, Pradeep K., Chodisetti, Sathi Babu, Zeng, Weiguang, Nadeem, Sajid, Maurya, Sudeep K., Pahari, Susanta, Janmeja, Ashok K., Jackson, David C., Agrewala, Javed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389088/
https://www.ncbi.nlm.nih.gov/pubmed/28985739
http://dx.doi.org/10.1186/s12967-017-1301-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389088/
https://www.ncbi.nlm.nih.gov/pubmed/28985739
http://dx.doi.org/10.1186/s12967-017-1301-x

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