Cargando…

Better ILP models for haplotype assembly

BACKGROUND: The haplotype assembly problem for diploid is to find a pair of haplotypes from a given set of aligned Single Nucleotide Polymorphism (SNP) fragments (reads). It has many applications in association studies, drug design, and genetic research. Since this problem is computationally hard, b...

Descripción completa

Detalles Bibliográficos
Autores principales: Etemadi, Maryam, Bagherian, Mehri, Chen, Zhi-Zhong, Wang, Lusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389102/
https://www.ncbi.nlm.nih.gov/pubmed/29504891
http://dx.doi.org/10.1186/s12859-018-2012-x