Cross-communication between G(i) and G(s) in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain

BACKGROUND: G-protein-coupled receptor (GPCR) heteromeric complexes have distinct properties from homomeric GPCRs, giving rise to new receptor functionalities. Adenosine receptors (A(1)R or A(2A)R) can form A(1)R-A(2A)R heteromers (A(1)-A(2A)Het), and their activation leads to canonical G-protein-de...

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Detalles Bibliográficos
Autores principales: Navarro, Gemma, Cordomí, Arnau, Brugarolas, Marc, Moreno, Estefanía, Aguinaga, David, Pérez-Benito, Laura, Ferre, Sergi, Cortés, Antoni, Casadó, Vicent, Mallol, Josefa, Canela, Enric I., Lluís, Carme, Pardo, Leonardo, McCormick, Peter J., Franco, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389107/
https://www.ncbi.nlm.nih.gov/pubmed/29486745
http://dx.doi.org/10.1186/s12915-018-0491-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389107/
https://www.ncbi.nlm.nih.gov/pubmed/29486745
http://dx.doi.org/10.1186/s12915-018-0491-x

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