The adjuvant G3 promotes a Th1 polarizing innate immune response in equine PBMC

The immunomodulatory effect of a new particulate adjuvant, G3, alone or in combination with agonists to TLR2/1 or TLR5 was evaluated in cultures of equine PBMC. Exposure to the G3 adjuvant up-regulated genes encoding IFN-γ, IL-1β, IL-6, IL-8, IL-12p40 and IL-23p19 in the majority of the horses teste...

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Detalles Bibliográficos
Autores principales: Hellman, Stina, Hjertner, Bernt, Morein, Bror, Fossum, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389152/
https://www.ncbi.nlm.nih.gov/pubmed/30348190
http://dx.doi.org/10.1186/s13567-018-0602-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389152/
https://www.ncbi.nlm.nih.gov/pubmed/30348190
http://dx.doi.org/10.1186/s13567-018-0602-2

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