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Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection

BACKGROUND: Avian influenza A H5N1 virus can cause lethal disease in humans. The virus can trigger severe pneumonia and lead to acute respiratory distress syndrome. Data from clinical, in vitro and in vivo suggest that virus-induced cytokine dysregulation could be a contributory factor to the pathog...

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Detalles Bibliográficos
Autores principales: Zhang, Na, Bao, Yun-Juan, Tong, Amy Hin-Yan, Zuyderduyn, Scott, Bader, Gary D., Malik Peiris, J. S., Lok, Si, Lee, Suki Man-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389164/
https://www.ncbi.nlm.nih.gov/pubmed/29475453
http://dx.doi.org/10.1186/s12920-018-0335-0