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The deregulated microRNAome contributes to the cellular response to aneuploidy

BACKGROUND: Aneuploidy, or abnormal chromosome numbers, severely alters cell physiology and is widespread in cancers and other pathologies. Using model cell lines engineered to carry one or more extra chromosomes, it has been demonstrated that aneuploidy per se impairs proliferation, leads to proteo...

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Detalles Bibliográficos
Autores principales: Dürrbaum, Milena, Kruse, Christine, Nieken, K. Julia, Habermann, Bianca, Storchová, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389165/
https://www.ncbi.nlm.nih.gov/pubmed/29703144
http://dx.doi.org/10.1186/s12864-018-4556-6