Individual retrotransposon integrants are differentially controlled by KZFP/KAP1-dependent histone methylation, DNA methylation and TET-mediated hydroxymethylation in naïve embryonic stem cells

BACKGROUND: The KZFP/KAP1 (KRAB zinc finger proteins/KRAB-associated protein 1) system plays a central role in repressing transposable elements (TEs) and maintaining parent-of-origin DNA methylation at imprinting control regions (ICRs) during the wave of genome-wide reprogramming that precedes impla...

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Detalles Bibliográficos
Autores principales: Coluccio, Andrea, Ecco, Gabriela, Duc, Julien, Offner, Sandra, Turelli, Priscilla, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389204/
https://www.ncbi.nlm.nih.gov/pubmed/29482634
http://dx.doi.org/10.1186/s13072-018-0177-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389204/
https://www.ncbi.nlm.nih.gov/pubmed/29482634
http://dx.doi.org/10.1186/s13072-018-0177-1

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