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Identification of two residues within the NS1 of H7N9 influenza A virus that critically affect the protein stability and function

The emerging avian-origin H7N9 influenza A virus, which causes mild to lethal human respiratory disease, continues to circulate in China, posing a great threat to public health. Influenza NS1 protein plays a key role in counteracting host innate immune responses, allowing the virus to efficiently re...

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Detalles Bibliográficos
Autores principales: Wang, Song, Zhang, Lanlan, Zhang, Rong, Chi, Xiaojuan, Yang, Zhou, Xie, Yanhui, Shu, Sicheng, Liao, Yuan, Chen, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389221/
https://www.ncbi.nlm.nih.gov/pubmed/30285871
http://dx.doi.org/10.1186/s13567-018-0594-y