Cargando…

Clinical significance of polyglutamylation in primary central nervous system lymphoma

The therapeutic response to high-dose methotrexate (HD-MTX) therapy for primary central nervous system lymphoma (PCNSL) varies. Polyglutamylation is a reversible protein modification with a high occurrence rate in tumor cells. MTX incorporated into cells is polyglutamylated and strongly binds to dih...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shinojima, Naoki, Fujimoto, Kenji, Makino, Keishi, Todaka, Kohei, Yamada, Kazumichi, Mikami, Yoshiki, Oda, Kazutaka, Nakamura, Kazumi, Jono, Hirofumi, Kuratsu, Jun-ichi, Nakamura, Hideo, Yano, Shigetoshi, Mukasa, Akitake
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389236/ https://www.ncbi.nlm.nih.gov/pubmed/29475458 http://dx.doi.org/10.1186/s40478-018-0522-4

Ejemplares similares

ML-03 RECONSIDERATION OF TREATMENT FOR ELDERLY PATIENTS WITH PRIMARY CENTRAL NERVE SYSTEM LYMPHOMAS
por: Shinojima, Naoki, et al.
Publicado: (2019)

Oligodendrocyte Progenitor Cells and Macrophages/Microglia Produce Glioma Stem Cell Niches at the Tumor Border
por: Hide, Takuichiro, et al.
Publicado: (2018)

GCT-36. TREATMENT RESULTS AND RADIATION-INDUCED TUMORS IN CASES OF CENTRAL NERVOUS SYSTEM GERM CELL TUMOR: A LONG-TERM FOLLOW-UP STUDY IN KUMAMOTO PREFECTURE
por: Yamamoto, Takahiro, et al.
Publicado: (2020)

Antitumor effect of fibrin glue containing temozolomide against malignant glioma
por: Anai, Shigeo, et al.
Publicado: (2014)

A case of suprasellar Erdheim-Chester disease and characterization of macrophage phenotype
por: Kai, Keitaro, et al.
Publicado: (2020)

ML-15 The future direction of treatment development for primary central nervous system lymphoma (PCNSL)
por: Shinojima, Naoki, et al.
Publicado: (2020)

Characteristics of brain metastases from esophageal carcinoma
por: Yamamoto, Takahiro, et al.
Publicado: (2014)

New Treatment Strategies to Eradicate Cancer Stem Cells and Niches in Glioblastoma
por: Hide, Takuichiro, et al.
Publicado: (2013)

Adult Diffuse Astrocytoma in the Medulla Oblongata: Molecular Biological Analyses Including H3F3A Mutation of Histone H3.3
por: Uekawa, Ken, et al.
Publicado: (2015)

MPC-16 RAPID PROGRESSIVE SPINAL DIFFUSE MIDLINE GLIOMA, A CASE REPORT
por: Takezaki, Tatsuya, et al.
Publicado: (2019)

EPID-01. TRENDS OF INCIDENCE IN PEDIATRIC BRAIN TUMORS IN KUMAMOTO PREFECTURE, JAPAN
por: Itoyama, Takashi, et al.
Publicado: (2020)

Endoscopic endonasal transsphenoidal surgery for patients aged over 80 years with pituitary adenomas: Surgical and follow-up results
por: Fujimoto, Kenji, et al.
Publicado: (2017)

EPEN-02. EVALUATION OF TREATMENT OUTCOMES AND EXPRESSION OF EMT-RELATED TRANSCRIPTION FACTORS AS NOVEL THERAPEUTIC TARGETS IN PEDIATRIC EPENDYMOMA
por: Makino, Keishi, et al.
Publicado: (2020)

ML-20 Outcome of high-dose methotrexate-based chemotherapy with or without Rituximab for primary central nervous system lymphoma
por: Takezaki, Tatsuya, et al.
Publicado: (2020)

A flexible endoscope-assisted interhemispheric transcallosal approach through the contralateral ventricle for the removal of a third ventricle craniopharyngioma: A technical report
por: Yano, Shigetoshi, et al.
Publicado: (2015)

Atypical pituitary abscess lacking rim enhancement and diffusion restriction with an unusual organism, Moraxella catarrhalis: A case report and review of the literature
por: Kawano, Tatsuya, et al.
Publicado: (2021)

CBMS-09 Intercellular communication at glioblastoma stem cell niches
por: Hide, Takuichiro, et al.
Publicado: (2020)

Endoscopic endonasal skull base approach for parasellar lesions: Initial experiences, results, efficacy, and complications
por: Yano, Shigetoshi, et al.
Publicado: (2014)

Histone deacetylase inhibition enhances the therapeutic effects of methotrexate on primary central nervous system lymphoma
por: Fujimoto, Kenji, et al.
Publicado: (2020)

CS-6 A case of poorly differentiated chordoma with systemic metastasis
por: Shinojima, Naoki, et al.
Publicado: (2021)

Polyglutamylation makes the cut
por: Short, Ben
Publicado: (2010)

Polyglutamylation: biology and analysis
por: Ruse, Cristian I., et al.
Publicado: (2022)

Ribosomal protein S6 promotes stem‐like characters in glioma cells
por: Shirakawa, Yuki, et al.
Publicado: (2020)

Prognostic value of isocitrate dehydrogenase 1, O(6)-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in Japanese malignant glioma patients
por: Takahashi, Yoshinobu, et al.
Publicado: (2013)

COT-18 Trends in Primary Brain Tumors in Kumamoto Prefecture with Declining Birthrate and Aging Population - Kumamoto Prefecture Brain Tumor Epidemiological Survey
por: Shinojima, Naoki, et al.
Publicado: (2021)

Monocyte chemoattractant protein 1 expression and proliferation in primary central nervous system lymphoma
por: Takahashi, Yoshinobu, et al.
Publicado: (2017)

Indocyanine Green Fluorescence Endoscopy at Endonasal Transsphenoidal Surgery for an Intracavernous Sinus Dermoid Cyst: Case Report
por: HIDE, Takuichiro, et al.
Publicado: (2014)

Gliosarcoma with Systemic Metastasis Showing Favorable Response to Ifosfamide, Carboplatin, and Etoposide Chemotherapy: An Autopsy Case Report
por: NAKAGAKI, Yuki, et al.
Publicado: (2022)

Skull Metastasis From Intrahepatic Cholangiocarcinoma: Report of 3 Cases and Review of the Literature
por: Fujimoto, Kenji, et al.
Publicado: (2013)

Giant tumefactive perivascular spaces that expanded and became symptomatic 14 years after initial surgery
por: Fujimoto, Kenji, et al.
Publicado: (2012)

Electrostatic interaction between polyglutamylated tubulin and the nexin–dynein regulatory complex regulates flagellar motility
por: Kubo, Tomohiro, et al.
Publicado: (2017)

A case of ecchordosis physaliphora presenting with an abducens nerve palsy: A rare symptomatic case managed with endoscopic endonasal transsphenoidal surgery
por: Yamamoto, Takahiro, et al.
Publicado: (2013)

CSF TACI and BAFF levels in patients with primary CNS lymphoma as novel diagnostic biomarkers
por: Mizutani, Hironori, et al.
Publicado: (2018)

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing
por: Lacroix, Benjamin, et al.
Publicado: (2010)

Reduced tubulin polyglutamylation suppresses flagellar shortness in Chlamydomonas
por: Kubo, Tomohiro, et al.
Publicado: (2015)

Tubulin polyglutamylation differentially regulates microtubule‐interacting proteins
por: Genova, Mariya, et al.
Publicado: (2023)

Benefit of 3T Diffusion-weighted Imaging in Comparison to Contrast-enhanced MR Imaging for the Evaluation of Disseminated Lesions in Primary Malignant Brain Tumors
por: Kadota, Yoshihito, et al.
Publicado: (2016)

Severe ciliopathy-related phenotypes in mice with dysregulation of tubulin polyglutamylation
por: Ikegami, K, et al.
Publicado: (2012)

Lynch syndrome-associated chordoma with high tumor mutational burden and significant response to immune checkpoint inhibitors
por: Shinojima, Naoki, et al.
Publicado: (2023)

ML-17 Clinical usefulness of Tirabrutinib in recurrent PCNSL: single institute experience
por: Matsuura, Jin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_id907leccmg7i9pgd3vtug4u9u