MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway

MicroRNA-122 (miR-122) is the most abundant microRNA in hepatocytes and a central player in liver biology and disease. Herein, we report a previously unknown role for miR-122 in hepatocyte intrinsic innate immunity. Restoration of miR-122 levels in hepatoma cells markedly enhanced the activation of...

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Detalles Bibliográficos
Autores principales: Xu, Hui, Xu, Shi-Jun, Xie, Shu-Juan, Zhang, Yin, Yang, Jian-Hua, Zhang, Wei-Qi, Zheng, Man-Ni, Zhou, Hui, Qu, Liang-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389286/
https://www.ncbi.nlm.nih.gov/pubmed/30735121
http://dx.doi.org/10.7554/eLife.41159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389286/
https://www.ncbi.nlm.nih.gov/pubmed/30735121
http://dx.doi.org/10.7554/eLife.41159

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