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Pleiotropy Modulates the Efficacy of Selection in Drosophila melanogaster

Pleiotropy is the well-established idea that a single mutation affects multiple phenotypes. If a mutation has opposite effects on fitness when expressed in different contexts, then genetic conflict arises. Pleiotropic conflict is expected to reduce the efficacy of selection by limiting the fixation...

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Detalles Bibliográficos
Autores principales: Fraïsse, Christelle, Puixeu Sala, Gemma, Vicoso, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389323/
https://www.ncbi.nlm.nih.gov/pubmed/30590559
http://dx.doi.org/10.1093/molbev/msy246