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Pleiotropy Modulates the Efficacy of Selection in Drosophila melanogaster
Pleiotropy is the well-established idea that a single mutation affects multiple phenotypes. If a mutation has opposite effects on fitness when expressed in different contexts, then genetic conflict arises. Pleiotropic conflict is expected to reduce the efficacy of selection by limiting the fixation...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389323/ https://www.ncbi.nlm.nih.gov/pubmed/30590559 http://dx.doi.org/10.1093/molbev/msy246 |