The Impact and Mechanism of a Novel Allosteric AMPA Receptor Modulator LCX001 on Protection Against Respiratory Depression in Rodents

Analgesics and sedative hypnotics in clinical use often give rise to significant side effects, particularly respiratory depression. For emergency use, specific antagonists are currently administered to counteract respiratory depression. However, antagonists are often short-lasting and eliminate drug...

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Detalles Bibliográficos
Autores principales: Dai, Wei, Gao, Xiang, Xiao, Dian, Li, Yu-Lei, Zhou, Xin-Bo, Yong, Zheng, Su, Rui-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389625/
https://www.ncbi.nlm.nih.gov/pubmed/30837875
http://dx.doi.org/10.3389/fphar.2019.00105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389625/
https://www.ncbi.nlm.nih.gov/pubmed/30837875
http://dx.doi.org/10.3389/fphar.2019.00105

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