Cargando…
Requirement for Cyclic AMP/Protein Kinase A-Dependent Canonical NFκB Signaling in the Adjuvant Action of Cholera Toxin and Its Non-toxic Derivative mmCT
Cholera toxin (CT) is widely used as an effective adjuvant in experimental immunology for inducing mucosal immune responses; yet its mechanisms of adjuvant action remain incompletely defined. Here, we demonstrate that mice lacking NFκB, compared to wild-type (WT) mice, had a 90% reduction in their s...
Autores principales: | Terrinoni, Manuela, Holmgren, Jan, Lebens, Michael, Larena, Maximilian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389712/ https://www.ncbi.nlm.nih.gov/pubmed/30838003 http://dx.doi.org/10.3389/fimmu.2019.00269 |
Ejemplares similares
-
Proteomic analysis of cholera toxin adjuvant-stimulated human monocytes identifies Thrombospondin-1 and Integrin-β1 as strongly upregulated molecules involved in adjuvant activity
por: Terrinoni, Manuela, et al.
Publicado: (2019) -
Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin
por: Sun, Jia-Bin, et al.
Publicado: (2017) -
A Novel Nonantibiotic, lgt-Based Selection System for Stable Maintenance of Expression Vectors in Escherichia coli and Vibrio cholerae
por: Terrinoni, Manuela, et al.
Publicado: (2018) -
The adjuvants dmLT and mmCT enhance humoral immune responses to a pneumococcal conjugate vaccine after both parenteral or mucosal immunization of neonatal mice
por: Molina Estupiñan, Jenny Lorena, et al.
Publicado: (2023) -
The microarray manual curation tool (MMCT): A Web server for microarray probe evaluations
por: Tulpan, Dan, et al.
Publicado: (2010)