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A Comparative Study of Cluster Detection Algorithms in Protein–Protein Interaction for Drug Target Discovery and Drug Repurposing

The interactions between drugs and their target proteins induce altered expression of genes involved in complex intracellular networks. The properties of these functional network modules are critical for the identification of drug targets, for drug repurposing, and for understanding the underlying m...

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Detalles Bibliográficos
Autores principales: Ma, Jun, Wang, Jenny, Ghoraie, Laleh Soltan, Men, Xin, Haibe-Kains, Benjamin, Dai, Penggao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389713/
https://www.ncbi.nlm.nih.gov/pubmed/30837876
http://dx.doi.org/10.3389/fphar.2019.00109