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A Comparative Study of Cluster Detection Algorithms in Protein–Protein Interaction for Drug Target Discovery and Drug Repurposing
The interactions between drugs and their target proteins induce altered expression of genes involved in complex intracellular networks. The properties of these functional network modules are critical for the identification of drug targets, for drug repurposing, and for understanding the underlying m...
Autores principales: | Ma, Jun, Wang, Jenny, Ghoraie, Laleh Soltan, Men, Xin, Haibe-Kains, Benjamin, Dai, Penggao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389713/ https://www.ncbi.nlm.nih.gov/pubmed/30837876 http://dx.doi.org/10.3389/fphar.2019.00109 |
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