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Carbon Acidity in Enzyme Active Sites
The pK(a) values for substrates acting as carbon acids (i.e., C-H deprotonation reactions) in several enzyme active sites are presented. The information needed to calculate them includes the pK(a) of the active site acid/base catalyst and the equilibrium constant for the deprotonation step. Carbon a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389717/ https://www.ncbi.nlm.nih.gov/pubmed/30838206 http://dx.doi.org/10.3389/fbioe.2019.00025 |