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Humanized Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Cell-Based Therapies

Rodent models of rheumatoid arthritis (RA) have been used over decades to study the immunopathogenesis of the disease and to explore intervention strategies. Nevertheless, mouse models of RA reach their limit when it comes to testing of new therapeutic approaches such as cell-based therapies. Differ...

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Detalles Bibliográficos
Autores principales: Schinnerling, Katina, Rosas, Carlos, Soto, Lilian, Thomas, Ranjeny, Aguillón, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389733/
https://www.ncbi.nlm.nih.gov/pubmed/30837986
http://dx.doi.org/10.3389/fimmu.2019.00203