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Antemortem CSF Aβ42/Aβ40 ratio predicts Alzheimer's disease pathology better than Aβ42 in rapidly progressive dementias

OBJECTIVE: Despite the critical importance of pathologically confirmed samples for biomarker validation, only a few studies have correlated CSF Aβ42 values in vivo with postmortem Alzheimer's disease (AD) pathology, while none evaluated the CSF Aβ42/Aβ40 ratio. We compared CSF Aβ42 and Aβ42/Aβ4...

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Detalles Bibliográficos
Autores principales: Baiardi, Simone, Abu‐Rumeileh, Samir, Rossi, Marcello, Zenesini, Corrado, Bartoletti‐Stella, Anna, Polischi, Barbara, Capellari, Sabina, Parchi, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389744/
https://www.ncbi.nlm.nih.gov/pubmed/30847359
http://dx.doi.org/10.1002/acn3.697