Cargando…
Antemortem CSF Aβ42/Aβ40 ratio predicts Alzheimer's disease pathology better than Aβ42 in rapidly progressive dementias
OBJECTIVE: Despite the critical importance of pathologically confirmed samples for biomarker validation, only a few studies have correlated CSF Aβ42 values in vivo with postmortem Alzheimer's disease (AD) pathology, while none evaluated the CSF Aβ42/Aβ40 ratio. We compared CSF Aβ42 and Aβ42/Aβ4...
Autores principales: | Baiardi, Simone, Abu‐Rumeileh, Samir, Rossi, Marcello, Zenesini, Corrado, Bartoletti‐Stella, Anna, Polischi, Barbara, Capellari, Sabina, Parchi, Piero |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389744/ https://www.ncbi.nlm.nih.gov/pubmed/30847359 http://dx.doi.org/10.1002/acn3.697 |
Ejemplares similares
-
CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia
por: Abu-Rumeileh, Samir, et al.
Publicado: (2019) -
The characterization of AD/PART co-pathology in CJD suggests independent pathogenic mechanisms and no cross-seeding between misfolded Aβ and prion proteins
por: Rossi, Marcello, et al.
Publicado: (2019) -
Prion-specific and surrogate CSF biomarkers in Creutzfeldt-Jakob disease: diagnostic accuracy in relation to molecular subtypes and analysis of neuropathological correlates of p-tau and Aβ42 levels
por: Lattanzio, Francesca, et al.
Publicado: (2017) -
Diagnostic and prognostic performance of CSF α‐synuclein in prion disease in the context of rapidly progressive dementia
por: Mastrangelo, Andrea, et al.
Publicado: (2021) -
CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease
por: Janelidze, Shorena, et al.
Publicado: (2016)