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In vivo evidence for pre‐symptomatic neuroinflammation in a MAPT mutation carrier

Neuroinflammation occurs in frontotemporal dementia, however its timing relative to protein aggregation and neuronal loss is unknown. Using positron emission tomography and magnetic resonance imaging to quantify these processes in a pre‐symptomatic carrier of the 10 + 16 MAPT mutation, we show micro...

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Detalles Bibliográficos
Autores principales: Bevan‐Jones, W. Richard, Cope, Thomas E., Jones, P. Simon, Passamonti, Luca, Hong, Young T., Fryer, Tim, Arnold, Robert, Coles, Jonathan P., Aigbirhio, Franklin I., O'Brien, John T., Rowe, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389753/
https://www.ncbi.nlm.nih.gov/pubmed/30847369
http://dx.doi.org/10.1002/acn3.683