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In vivo evidence for pre‐symptomatic neuroinflammation in a MAPT mutation carrier
Neuroinflammation occurs in frontotemporal dementia, however its timing relative to protein aggregation and neuronal loss is unknown. Using positron emission tomography and magnetic resonance imaging to quantify these processes in a pre‐symptomatic carrier of the 10 + 16 MAPT mutation, we show micro...
Autores principales: | Bevan‐Jones, W. Richard, Cope, Thomas E., Jones, P. Simon, Passamonti, Luca, Hong, Young T., Fryer, Tim, Arnold, Robert, Coles, Jonathan P., Aigbirhio, Franklin I., O'Brien, John T., Rowe, James B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389753/ https://www.ncbi.nlm.nih.gov/pubmed/30847369 http://dx.doi.org/10.1002/acn3.683 |
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