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Characterization and structure‐guided engineering of the novel versatile terpene monooxygenase CYP109Q5 from Chondromyces apiculatus DSM436

One of the major challenges in chemical synthesis is the selective oxyfunctionalization of non‐activated C‐H bonds, which can be enabled by biocatalysis using cytochrome P450 monooxygenases. In this study, we report on the characterization of the versatile CYP109Q5 from Chondromyces apiculatus DSM43...

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Detalles Bibliográficos
Autores principales: Klenk, Jan M., Dubiel, Paulina, Sharma, Mahima, Grogan, Gideon, Hauer, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389848/
https://www.ncbi.nlm.nih.gov/pubmed/30592153
http://dx.doi.org/10.1111/1751-7915.13354