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Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

Several Genome Wide Association Studies (GWAS) have reported variants associated to immune diseases. However, the identified variants are rarely the drivers of the associations and the molecular mechanisms behind the genetic contributions remain poorly understood. ChIP-seq data for TFs and histone m...

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Detalles Bibliográficos
Autores principales: Cavalli, Marco, Baltzer, Nicholas, Umer, Husen M., Grau, Jan, Lemnian, Ioana, Pan, Gang, Wallerman, Ola, Spalinskas, Rapolas, Sahlén, Pelin, Grosse, Ivo, Komorowski, Jan, Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389883/
https://www.ncbi.nlm.nih.gov/pubmed/30804403
http://dx.doi.org/10.1038/s41598-019-39633-0