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Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal bonding behaviours. Mice lacking secreted oxcytocin (Oxt(−/−), Cd38(−/−)) or its receptor (Oxtr(−/−)) fail to nurture. Normal maternal behaviour is restored by peripheral oxcytocin replacement in Oxt(−/...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389896/ https://www.ncbi.nlm.nih.gov/pubmed/30820471 http://dx.doi.org/10.1038/s42003-019-0325-6 |