Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice

Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal bonding behaviours. Mice lacking secreted oxcytocin (Oxt(−/−), Cd38(−/−)) or its receptor (Oxtr(−/−)) fail to nurture. Normal maternal behaviour is restored by peripheral oxcytocin replacement in Oxt(−/...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yasuhiko, Liang, Mingkun, Munesue, Seiichi, Deguchi, Kisaburo, Harashima, Ai, Furuhara, Kazumi, Yuhi, Teruko, Zhong, Jing, Akther, Shirin, Goto, Hisanori, Eguchi, Yuya, Kitao, Yasuko, Hori, Osamu, Shiraishi, Yoshitake, Ozaki, Noriyuki, Shimizu, Yu, Kamide, Tomoya, Yoshikawa, Akifumi, Hayashi, Yasuhiko, Nakada, Mitsutoshi, Lopatina, Olga, Gerasimenko, Maria, Komleva, Yulia, Malinovskaya, Natalia, Salmina, Alla B., Asano, Masahide, Nishimori, Katsuhiko, Shoelson, Steven E., Yamamoto, Hiroshi, Higashida, Haruhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389896/
https://www.ncbi.nlm.nih.gov/pubmed/30820471
http://dx.doi.org/10.1038/s42003-019-0325-6

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