Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

Pyroptosis, a form of programmed cell death (PCD), has garnered increasing attention as it relates to innate immunity and diseases. However, the involvement of pyroptosis in the mechanism by which lobaplatin acts against colorectal cancer (CRC) is unclear. Our study revealed that treatment with loba...

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Detalles Bibliográficos
Autores principales: Yu, Junhui, Li, Shan, Qi, Jie, Chen, Zilu, Wu, Yunhua, Guo, Jing, Wang, Kai, Sun, Xuejun, Zheng, Jianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389936/
https://www.ncbi.nlm.nih.gov/pubmed/30804337
http://dx.doi.org/10.1038/s41419-019-1441-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389936/
https://www.ncbi.nlm.nih.gov/pubmed/30804337
http://dx.doi.org/10.1038/s41419-019-1441-4

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