Assembly and functionality of the ribosome with tethered subunits

Ribo-T is an engineered ribosome whose small and large subunits are tethered together by linking 16S rRNA and 23S rRNA in a single molecule. Although Ribo-T can support cell proliferation in the absence of wild type ribosomes, Ribo-T cells grow slower than those with wild type ribosomes. Here, we sh...

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Detalles Bibliográficos
Autores principales: Aleksashin, Nikolay A., Leppik, Margus, Hockenberry, Adam J., Klepacki, Dorota, Vázquez-Laslop, Nora, Jewett, Michael C., Remme, Jaanus, Mankin, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389949/
https://www.ncbi.nlm.nih.gov/pubmed/30804338
http://dx.doi.org/10.1038/s41467-019-08892-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389949/
https://www.ncbi.nlm.nih.gov/pubmed/30804338
http://dx.doi.org/10.1038/s41467-019-08892-w

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