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Pancreatic acinar differentiation is guided by differential laminin deposition

Endothelial cells play multiple roles during pancreas organogenesis. First, they are required to instruct endoderm-derived pancreatic progenitor cells to initiate branching morphogenesis. Later, blood vessels promote β-cell differentiation but also limit acinar development. In this work, we show how...

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Detalles Bibliográficos
Autores principales: Heymans, Charlotte, Degosserie, Jonathan, Spourquet, Catherine, Pierreux, Christophe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389953/
https://www.ncbi.nlm.nih.gov/pubmed/30804366
http://dx.doi.org/10.1038/s41598-019-39077-6