Downregulation of M-channels in lateral habenula mediates hyperalgesia during alcohol withdrawal in rats

Hyperalgesia often occurs in alcoholics, especially during abstinence, yet the underlying mechanisms remain elusive. The lateral habenula (LHb) has been implicated in the pathophysiology of pain and alcohol use disorders. Suppression of m-type potassium channels (M-channels) has been found to contri...

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Detalles Bibliográficos
Autores principales: Kang, Seungwoo, Li, Jing, Zuo, Wanhong, Chen, Pei, Gregor, Danielle, Fu, Rao, Han, Xiao, Bekker, Alex, Ye, Jiang-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389965/
https://www.ncbi.nlm.nih.gov/pubmed/30804373
http://dx.doi.org/10.1038/s41598-018-38393-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389965/
https://www.ncbi.nlm.nih.gov/pubmed/30804373
http://dx.doi.org/10.1038/s41598-018-38393-7

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