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Downregulation of M-channels in lateral habenula mediates hyperalgesia during alcohol withdrawal in rats
Hyperalgesia often occurs in alcoholics, especially during abstinence, yet the underlying mechanisms remain elusive. The lateral habenula (LHb) has been implicated in the pathophysiology of pain and alcohol use disorders. Suppression of m-type potassium channels (M-channels) has been found to contri...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389965/ https://www.ncbi.nlm.nih.gov/pubmed/30804373 http://dx.doi.org/10.1038/s41598-018-38393-7 |