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Molecular mechanism of lysophosphatidic acid-induced hypertensive response

Lysophosphatidic acid (LPA) is a blood-derived bioactive lipid with numerous biological activities exerted mainly through six defined G protein-coupled receptors (LPA(1)-LPA(6)). LPA was first identified as a vasoactive compound because it induced transient hypertension when injected intravenously i...

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Detalles Bibliográficos
Autores principales: Kano, Kuniyuki, Matsumoto, Hirotaka, Inoue, Asuka, Yukiura, Hiroshi, Kanai, Motomu, Chun, Jerold, Ishii, Satoshi, Shimizu, Takao, Aoki, Junken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389983/
https://www.ncbi.nlm.nih.gov/pubmed/30804442
http://dx.doi.org/10.1038/s41598-019-39041-4