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Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia

Preeclampsia is a pregnancy-specific disorder that is a major cause of maternal and fetal morbidity and mortality with a prevalence of 6–8% of pregnancies. Although impaired trophoblast invasion in early pregnancy is known to be closely associated with preeclampsia, the underlying mechanisms remain...

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Detalles Bibliográficos
Autores principales: Xu, Xiang-Hong, Jia, Yuanhui, Zhou, Xinyao, Xie, Dandan, Huang, Xiaojie, Jia, Linyan, Zhou, Qian, Zheng, Qingliang, Zhou, Xiangyu, Wang, Kai, Jin, Li-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389995/
https://www.ncbi.nlm.nih.gov/pubmed/30804321
http://dx.doi.org/10.1038/s12276-019-0211-9