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Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression-independent manner in HPV-positive human cervical cancer-derived cells

Cervical cancer is the second most common cancer in women worldwide. Human papillomavirus (HPV) infection appears to be a necessary factor in the development of almost all cases (>95%) of cervical cancer. HPV E6 induces a change of control of p53 stabilization from Hdm2 to E6/E6AP in HPV-infected...

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Detalles Bibliográficos
Autores principales: Clemente-Soto, Aldo F., Salas-Vidal, Enrique, Milan-Pacheco, Cesar, Sánchez-Carranza, Jessica Nayelli, Peralta-Zaragoza, Oscar, González-Maya, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390007/
https://www.ncbi.nlm.nih.gov/pubmed/30664221
http://dx.doi.org/10.3892/mmr.2019.9850