Sodium azide induces mitochondria-mediated apoptosis in PC12 cells through Pgc-1α-associated signaling pathway

Sodium azide (NaN(3)), an inhibitor of cytochrome oxidase, induces the release of excitotoxins via an energy impairment and this, in turn, results in neurodegeneration. The present study aimed to investigate the toxic effects NaN(3) on apoptosis of PC12 cells and its mechanism of action in peroxisom...

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Detalles Bibliográficos
Autores principales: Zuo, Yuanyi, Hu, Jun, Xu, Xuehua, Gao, Xiangting, Wang, Yun, Zhu, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390015/
https://www.ncbi.nlm.nih.gov/pubmed/30664159
http://dx.doi.org/10.3892/mmr.2019.9853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390015/
https://www.ncbi.nlm.nih.gov/pubmed/30664159
http://dx.doi.org/10.3892/mmr.2019.9853

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