NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology

OBJECTIVES: NFIL3 is a key immunological transcription factor, with knockout mice studies identifying functional roles in multiple immune cell types. Despite the importance of NFIL3, little is known about its function in humans. METHODS: Here, we characterised a kindred of two monozygotic twin girls...

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Detalles Bibliográficos
Autores principales: Schlenner, Susan, Pasciuto, Emanuela, Lagou, Vasiliki, Burton, Oliver, Prezzemolo, Teresa, Junius, Steffie, Roca, Carlos P, Seillet, Cyril, Louis, Cynthia, Dooley, James, Luong, Kylie, Van Nieuwenhove, Erika, Wicks, Ian P, Belz, Gabrielle, Humblet-Baron, Stéphanie, Wouters, Carine, Liston, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Rheumatoid Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390028/
https://www.ncbi.nlm.nih.gov/pubmed/30552177
http://dx.doi.org/10.1136/annrheumdis-2018-213764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390028/
https://www.ncbi.nlm.nih.gov/pubmed/30552177
http://dx.doi.org/10.1136/annrheumdis-2018-213764

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