Long noncoding RNA GAS5 promotes apoptosis in primary nucleus pulposus cells derived from the human intervertebral disc via Bcl-2 downregulation and caspase-3 upregulation

Nucleus pulposus cell (NPC) apoptosis serves an important role in intervertebral disc degeneration (IDD); however, the roles of long noncoding RNAs (lncRNAs) in this process remain unknown. The present study aimed to determine the effects of the lncRNA growth arrest-specific transcript 5 (GAS5) on t...

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Detalles Bibliográficos
Autores principales: Wang, Yifeng, Song, Qingxin, Huang, Xuan, Chen, Zhi, Zhang, Fan, Wang, Kun, Huang, Guofeng, Shen, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390029/
https://www.ncbi.nlm.nih.gov/pubmed/30747227
http://dx.doi.org/10.3892/mmr.2019.9883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390029/
https://www.ncbi.nlm.nih.gov/pubmed/30747227
http://dx.doi.org/10.3892/mmr.2019.9883

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