Butyl stearate prolongs the drug release period of isoperidone-loaded poly (lactic-co-glycolic acid) microspheres: In vitro and in vivo investigation

The present study aimed to investigate the effects of butyl stearate on t-butoxyl paliperidone derivative (isoperidone)-loaded poly(lactide-co-glycolide) (PLGA) microspheres. The mechanism of drug release rate delay by butyl stearate was examined by accelerated testing, morphological observation, th...

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Detalles Bibliográficos
Autores principales: Sun, Fengying, Yu, Changhui, Liu, Ximing, Wang, Dan, Liu, Na, Liu, Jiaxin, Teng, Lesheng, Li, Youxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390036/
https://www.ncbi.nlm.nih.gov/pubmed/30592277
http://dx.doi.org/10.3892/mmr.2018.9797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390036/
https://www.ncbi.nlm.nih.gov/pubmed/30592277
http://dx.doi.org/10.3892/mmr.2018.9797

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