Ticagrelor suppresses oxidized low-density lipoprotein-induced endothelial cell apoptosis and alleviates atherosclerosis in ApoE(−/−) mice via downregulation of PCSK9

Although ticagrelor has been demonstrated to possess an anti-atherosclerosis (AS) effect, its underlying mechanism remains unclear. In the present study, it was investigated whether ticagrelor reduces oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell apoptosis, an initial step for t...

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Detalles Bibliográficos
Autores principales: Xia, Xiaodong, Li, Jiao, Liang, Xue, Zhang, Shengjie, Liu, Tong, Liu, Jinying, Arif, Muhammad, Li, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390053/
https://www.ncbi.nlm.nih.gov/pubmed/30592271
http://dx.doi.org/10.3892/mmr.2018.9779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390053/
https://www.ncbi.nlm.nih.gov/pubmed/30592271
http://dx.doi.org/10.3892/mmr.2018.9779

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