Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide-induced lung injury

Epithelial sodium channel (ENaC) provides the driving force for the removal of edema from the alveolar spaces in acute lung injury (ALI). Our previous study reported that insulin increased the expression of α-ENaC, possibly via the serum/glucocorticoid-inducible kinase-1 (SGK1) pathway in ALI; howev...

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Detalles Bibliográficos
Autores principales: Deng, Wang, Li, Chang-Yi, Tong, Jin, He, Jing, Zhao, Yan, Wang, Dao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390057/
https://www.ncbi.nlm.nih.gov/pubmed/30628684
http://dx.doi.org/10.3892/mmr.2019.9809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390057/
https://www.ncbi.nlm.nih.gov/pubmed/30628684
http://dx.doi.org/10.3892/mmr.2019.9809

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