A molecular mechanism for transthyretin amyloidogenesis

Human transthyretin (TTR) is implicated in several fatal forms of amyloidosis. Many mutations of TTR have been identified; most of these are pathogenic, but some offer protective effects. The molecular basis underlying the vastly different fibrillation behaviours of these TTR mutants is poorly under...

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Detalles Bibliográficos
Autores principales: Yee, Ai Woon, Aldeghi, Matteo, Blakeley, Matthew P., Ostermann, Andreas, Mas, Philippe J., Moulin, Martine, de Sanctis, Daniele, Bowler, Matthew W., Mueller-Dieckmann, Christoph, Mitchell, Edward P., Haertlein, Michael, de Groot, Bert L., Boeri Erba, Elisabetta, Forsyth, V. Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390107/
https://www.ncbi.nlm.nih.gov/pubmed/30804345
http://dx.doi.org/10.1038/s41467-019-08609-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390107/
https://www.ncbi.nlm.nih.gov/pubmed/30804345
http://dx.doi.org/10.1038/s41467-019-08609-z

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