A molecular mechanism for transthyretin amyloidogenesis

Human transthyretin (TTR) is implicated in several fatal forms of amyloidosis. Many mutations of TTR have been identified; most of these are pathogenic, but some offer protective effects. The molecular basis underlying the vastly different fibrillation behaviours of these TTR mutants is poorly under...

Descripción completa

Detalles Bibliográficos
Autores principales: Yee, Ai Woon, Aldeghi, Matteo, Blakeley, Matthew P., Ostermann, Andreas, Mas, Philippe J., Moulin, Martine, de Sanctis, Daniele, Bowler, Matthew W., Mueller-Dieckmann, Christoph, Mitchell, Edward P., Haertlein, Michael, de Groot, Bert L., Boeri Erba, Elisabetta, Forsyth, V. Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390107/
https://www.ncbi.nlm.nih.gov/pubmed/30804345
http://dx.doi.org/10.1038/s41467-019-08609-z

Ejemplares similares

Ejemplares similares