Functionality of membrane proteins overexpressed and purified from E. coli is highly dependent upon the strain

Overexpression of correctly folded membrane proteins is a fundamental prerequisite for functional and structural studies. One of the most commonly used expression systems for the production of membrane proteins is Escherichia coli. While misfolded proteins typically aggregate and form inclusions bod...

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Detalles Bibliográficos
Autores principales: Mathieu, Khadija, Javed, Waqas, Vallet, Sylvain, Lesterlin, Christian, Candusso, Marie-Pierre, Ding, Feng, Xu, Xiaohong Nancy, Ebel, Christine, Jault, Jean-Michel, Orelle, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390180/
https://www.ncbi.nlm.nih.gov/pubmed/30804404
http://dx.doi.org/10.1038/s41598-019-39382-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390180/
https://www.ncbi.nlm.nih.gov/pubmed/30804404
http://dx.doi.org/10.1038/s41598-019-39382-0

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