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Neuroinflammation and central PI3K/Akt/mTOR signal pathway contribute to bone cancer pain

BACKGROUND: Pain is one of the most common and distressing symptoms suffered by patients with progression of cancer; however, the mechanisms responsible for hyperalgesia are not well understood. Since the midbrain periaqueductal gray is an important component of the descending inhibitory pathway con...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Wang, Luping, Wang, Hushan, Su, Zhenbo, Pang, Xiaochuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390230/
https://www.ncbi.nlm.nih.gov/pubmed/30717619
http://dx.doi.org/10.1177/1744806919830240