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Neuroinflammation and central PI3K/Akt/mTOR signal pathway contribute to bone cancer pain
BACKGROUND: Pain is one of the most common and distressing symptoms suffered by patients with progression of cancer; however, the mechanisms responsible for hyperalgesia are not well understood. Since the midbrain periaqueductal gray is an important component of the descending inhibitory pathway con...
Autores principales: | Zhang, Jian, Wang, Luping, Wang, Hushan, Su, Zhenbo, Pang, Xiaochuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390230/ https://www.ncbi.nlm.nih.gov/pubmed/30717619 http://dx.doi.org/10.1177/1744806919830240 |
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