miR-195-5p/NOTCH2-mediated EMT modulates IL-4 secretion in colorectal cancer to affect M2-like TAM polarization

BACKGROUND: Tumor microenvironment (TME) is a complex environment containing tumor cells, tumor-associated macrophages (TAMs), interstitial cells, and non-cellular components. Epithelial–mesenchymal transition (EMT), as a major actor in cancer tumorigenicity and metastasis, was involved in the inter...

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Detalles Bibliográficos
Autores principales: Lin, Xiaobin, Wang, Shuyi, Sun, Min, Zhang, Chunxiao, Wei, Chen, Yang, Chaogang, Dou, Rongzhang, Liu, Qing, Xiong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390326/
https://www.ncbi.nlm.nih.gov/pubmed/30808369
http://dx.doi.org/10.1186/s13045-019-0708-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390326/
https://www.ncbi.nlm.nih.gov/pubmed/30808369
http://dx.doi.org/10.1186/s13045-019-0708-7

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