Affinity depletion versus relative protein enrichment: a side-by-side comparison of two major strategies for increasing human cerebrospinal fluid proteome coverage

Cerebrospinal fluid (CSF) is in direct contact with the central nervous system. This makes human CSF an attractive source of potential biomarkers for neurologic diseases. Similarly to blood plasma, proteomic analysis of CSF is complicated by a high dynamic range of individual protein concentrations...

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Detalles Bibliográficos
Autores principales: Jankovska, Eliska, Svitek, Marek, Holada, Karel, Petrak, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390343/
https://www.ncbi.nlm.nih.gov/pubmed/30890900
http://dx.doi.org/10.1186/s12014-019-9229-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390343/
https://www.ncbi.nlm.nih.gov/pubmed/30890900
http://dx.doi.org/10.1186/s12014-019-9229-1

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