HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia

BACKGROUND: HIF1A (Hypoxia-Inducible-Factor 1A) expression in solid tumors is relevant to establish resistance to therapeutic approaches. The use of compounds direct against hypoxia signaling and HIF1A does not show clinical efficiency because of changeable oxygen concentrations in solid tumor areas...

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Detalles Bibliográficos
Autores principales: Cimmino, Flora, Avitabile, Marianna, Lasorsa, Vito Alessandro, Montella, Annalaura, Pezone, Lucia, Cantalupo, Sueva, Visconte, Feliciano, Corrias, Maria Valeria, Iolascon, Achille, Capasso, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390360/
https://www.ncbi.nlm.nih.gov/pubmed/30808328
http://dx.doi.org/10.1186/s12881-019-0767-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390360/
https://www.ncbi.nlm.nih.gov/pubmed/30808328
http://dx.doi.org/10.1186/s12881-019-0767-1

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